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Metabolomic profiling in a Hedgehog Interacting Protein (Hhip) murine model of chronic obstructive pulmonary disease

Genetic variants annotated to the hedgehog interacting protein (HHIP) are robustly associated with chronic obstructive pulmonary disease (COPD). Hhip haploinsufficiency in mice leads to increased susceptibility towards the development of emphysema following exposure to chronic cigarette smoke (CS)....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wan, Emily S., Li, Yan, Lao, Taotao, Qiu, Weiliang, Jiang, Zhiqiang, Mancini, John D., Owen, Caroline A., Clish, Clary, DeMeo, Dawn L., Silverman, Edwin K., Zhou, Xiaobo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451406/
https://ncbi.nlm.nih.gov/pubmed/28566717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02701-4
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