Metabolomic profiling in a Hedgehog Interacting Protein (Hhip) murine model of chronic obstructive pulmonary disease

Genetic variants annotated to the hedgehog interacting protein (HHIP) are robustly associated with chronic obstructive pulmonary disease (COPD). Hhip haploinsufficiency in mice leads to increased susceptibility towards the development of emphysema following exposure to chronic cigarette smoke (CS)....

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Udgivet i:Sci Rep
Main Authors: Wan, Emily S., Li, Yan, Lao, Taotao, Qiu, Weiliang, Jiang, Zhiqiang, Mancini, John D., Owen, Caroline A., Clish, Clary, DeMeo, Dawn L., Silverman, Edwin K., Zhou, Xiaobo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451406/
https://ncbi.nlm.nih.gov/pubmed/28566717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02701-4
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