Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP

Multiple intergenic single-nucleotide polymorphisms (SNPs) near hedgehog interacting protein (HHIP) on chromosome 4q31 have been strongly associated with pulmonary function levels and moderate-to-severe chronic obstructive pulmonary disease (COPD). However, whether the effects of variants in this re...

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Hlavní autoři: Zhou, Xiaobo, Baron, Rebecca M., Hardin, Megan, Cho, Michael H., Zielinski, Jan, Hawrylkiewicz, Iwona, Sliwinski, Pawel, Hersh, Craig P., Mancini, John D., Lu, Ke, Thibault, Derek, Donahue, Amy L., Klanderman, Barbara J., Rosner, Bernard, Raby, Benjamin A., Lu, Quan, Geldart, Adriana M., Layne, Matthew D., Perrella, Mark A., Weiss, Scott T., Choi, Augustine M.K., Silverman, Edwin K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284120/
https://ncbi.nlm.nih.gov/pubmed/22140090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr569
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