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Dual Beneficial Effect of Interloop Disulfide Bond for Single Domain Antibody Fragments
The antigen-binding fragment of functional heavy chain antibodies (HCAbs) in camelids comprises a single domain, named the variable domain of heavy chain of HCAbs (VHH). The VHH harbors remarkable amino acid substitutions in the framework region-2 to generate an antigen-binding domain that functions...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3283254/ https://ncbi.nlm.nih.gov/pubmed/22128183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.242818 |
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