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Plasmacytoid Dendritic Cells Sequester High Prion Titres at Early Stages of Prion Infection

In most transmissible spongiform encephalopathies prions accumulate in the lymphoreticular system (LRS) long before they are detectable in the central nervous system. While a considerable body of evidence showed that B lymphocytes and follicular dendritic cells play a major role in prion colonizatio...

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Hlavní autoři: Castro-Seoane, Rocio, Hummerich, Holger, Sweeting, Trevor, Tattum, M. Howard, Linehan, Jacqueline M., Fernandez de Marco, Mar, Brandner, Sebastian, Collinge, John, Klöhn, Peter-Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280992/
https://ncbi.nlm.nih.gov/pubmed/22359509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002538
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