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Plasmacytoid Dendritic Cells Sequester High Prion Titres at Early Stages of Prion Infection

In most transmissible spongiform encephalopathies prions accumulate in the lymphoreticular system (LRS) long before they are detectable in the central nervous system. While a considerable body of evidence showed that B lymphocytes and follicular dendritic cells play a major role in prion colonizatio...

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Detalhes bibliográficos
Main Authors: Castro-Seoane, Rocio, Hummerich, Holger, Sweeting, Trevor, Tattum, M. Howard, Linehan, Jacqueline M., Fernandez de Marco, Mar, Brandner, Sebastian, Collinge, John, Klöhn, Peter-Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280992/
https://ncbi.nlm.nih.gov/pubmed/22359509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002538
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