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The S4–S5 Linker Acts as a Signal Integrator for hERG K(+) Channel Activation and Deactivation Gating
Human ether-à-go-go-related gene (hERG) K(+) channels have unusual gating kinetics. Characterised by slow activation/deactivation but rapid inactivation/recovery from inactivation, the unique gating kinetics underlie the central role hERG channels play in cardiac repolarisation. The slow activation...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280985/ https://ncbi.nlm.nih.gov/pubmed/22359612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031640 |
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