Getting to the heart of hERG K(+) channel gating

Potassium ion channels encoded by the human ether-a-go-go related gene (hERG) form the ion-conducting subunit of the rapid delayed rectifier potassium current (I(Kr)). Although hERG channels exhibit a widespread tissue distribution they play a particularly important role in the heart. There has been...

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Bibliografiske detaljer
Udgivet i:J Physiol
Main Authors: Perry, Matthew D, Ng, Chai-Ann, Mann, Stefan A, Sadrieh, Arash, Imtiaz, Mohammad, Hill, Adam P, Vandenberg, Jamie I
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Symposium Section Reviews: Cutting-Edge Approaches Towards the Functioning Mechanisms of Membrane Proteins
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500344/
https://ncbi.nlm.nih.gov/pubmed/25820318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270095
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