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The crystal structure of the α-neurexin-1 extracellular region reveals a hinge point for mediating synaptic adhesion and function
α- and β-neurexins (NRXNs) are transmembrane cell adhesion proteins that localize to pre-synaptic membranes in neurons and interact with the post-synaptic neuroligins (NLGNs). Their gene mutations are associated with the autistic spectrum disorders. The extracellular region of α-NRXNs, containing ni...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3279696/ https://ncbi.nlm.nih.gov/pubmed/21620717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.03.011 |
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