Structural Analysis of the Synaptic Protein Neuroligin and Its β-Neurexin Complex: Determinants for Folding and Cell Adhesion

The neuroligins are postsynaptic cell adhesion proteins whose associations with presynaptic neurexins participate in synaptogenesis. Mutations in the neuroligin and neurexin genes appear to be associated with autism and mental retardation. The crystal structure of a neuroligin reveals features not f...

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Detalhes bibliográficos
Main Authors: Fabrichny, Igor P., Leone, Philippe, Sulzenbacher, Gerlind, Comoletti, Davide, Miller, Meghan T., Taylor, Palmer, Bourne, Yves, Marchot, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703725/
https://ncbi.nlm.nih.gov/pubmed/18093521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.11.013
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