Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions

The extracellular domains of neuroligins and neurexins interact through Ca(2+) to form flexible trans-synaptic associations characterized by selectivity for neuroligin or neurexin subtypes. This heterophilic interaction, essential for synaptic maturation and differentiation, is regulated by gene sel...

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Autors principals: Leone, Philippe, Comoletti, Davide, Ferracci, Géraldine, Conrod, Sandrine, Garcia, Simon U, Taylor, Palmer, Bourne, Yves, Marchot, Pascale
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910273/
https://ncbi.nlm.nih.gov/pubmed/20543817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.123
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