The macromolecular architecture of the extracellular domain of αNRXN1: domain organization, flexibility, and insights into trans-synaptic disposition

Neurexins are multi-domain synaptic cell-adhesion proteins that associate with multiple partnering proteins. Genetic evidence indicates that neurexins may contribute to autism, schizophrenia and nicotine dependence. Using analytical ultracentrifugation, single particle electron microscopy, and solut...

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Detaylı Bibliyografya
Asıl Yazarlar: Comoletti, Davide, Miller, Meghan, Jeffries, Cy M., Wilson, Jennifer, Demeler, Borries, Taylor, Palmer, Trewhella, Jill, Nakagawa, Terunaga
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948785/
https://ncbi.nlm.nih.gov/pubmed/20696403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.06.005
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