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In silico modification of suberoylanilide hydroxamic acid (SAHA) as potential inhibitor for class II histone deacetylase (HDAC)

BACKGROUND: The cervical cancer is the second most prevalent cancer for the woman in the world. It is caused by the oncogenic human papilloma virus (HPV). The inhibition activity of histone deacetylase (HDAC) is a potential strategy for cancer therapy. Suberoylanilide hydroxamic acid (SAHA) is widel...

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Détails bibliographiques
Auteurs principaux: Tambunan, Usman SF, Bramantya, N, Parikesit, Arli A
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278840/
https://ncbi.nlm.nih.gov/pubmed/22373132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S13-S23
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