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Molecular dynamics simulation of complex Histones Deacetylase (HDAC) Class II Homo Sapiens with suberoylanilide hydroxamic acid (SAHA) and its derivatives as inhibitors of cervical cancer

Cervical cancer is second most common cancer in woman worldwide. Cervical cancer caused by human papillomavirus (HPV) oncogene. Inhibition of histone deacetylase (HDAC) activity has been known as a potential strategy for cancer therapy. SAHA is an HDAC inhibitor that has been used in cancer therapy...

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Detalhes bibliográficos
Main Authors: Tambunan, Usman Sumo Friend, Bakri, Ridla, Prasetia, Tirtana, Parikesit, Arli Aditya, Kerami, Djati
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732443/
https://ncbi.nlm.nih.gov/pubmed/23930022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630009696
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