Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines

Included among the quantitative high throughput screens (qHTS) conducted in support of the U.S. Tox21 program are those being evaluated for the detection of genotoxic compounds. One such screen is based on the induction of increased cytotoxicity in 7 isogenic chicken DT40 cell lines deficient in DNA...

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Main Authors: Yamamoto, Kimiyo N., Hirota, Kouji, Kono, Koichi, Takeda, Shunichi, Sakamuru, Srilatha, Xia, Menghang, Huang, Ruili, Austin, Christopher P., Witt, Kristine L., Tice, Raymond R.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278799/
https://ncbi.nlm.nih.gov/pubmed/21538559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20656
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