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High-affinity fluorescent ligands for the 5-HT(3) receptor
The synthesis, photophysical and biological characterization of a small library of fluorescent 5-HT(3) receptor ligands is described. Several of these novel granisetron conjugates have high quantum yields and show high affinity for the human 5-HT(3)AR.
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science Ltd
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277886/ https://ncbi.nlm.nih.gov/pubmed/22189135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.11.097 |
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