Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-d-aspartate receptors

N-methyl-d-aspartate receptors (NMDARs) mediate critical CNS functions, whereas excessive activity contributes to neuronal damage. At physiological glycine concentrations, NMDAR currents recorded from cultured rodent hippocampal neurons exhibited strong desensitization in the continued presence of N...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: You, Haitao, Tsutsui, Shigeki, Hameed, Shahid, Kannanayakal, Thomas J., Chen, Lina, Xia, Peng, Engbers, Jordan D. T., Lipton, Stuart A., Stys, Peter K., Zamponi, Gerald W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277185/
https://ncbi.nlm.nih.gov/pubmed/22307640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110789109
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge