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Cellular prion protein and NMDA receptor modulation: protecting against excitotoxicity
Although it is well established that misfolding of the cellular prion protein (PrP(C)) into the β-sheet-rich, aggregated scrapie conformation (PrP(Sc)) causes a variety of transmissible spongiform encephalopathies (TSEs), the physiological roles of PrP(C) are still incompletely understood. There is...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4207032/ https://ncbi.nlm.nih.gov/pubmed/25364752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00045 |
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