Cellular prion protein and NMDA receptor modulation: protecting against excitotoxicity

Although it is well established that misfolding of the cellular prion protein (PrP(C)) into the β-sheet-rich, aggregated scrapie conformation (PrP(Sc)) causes a variety of transmissible spongiform encephalopathies (TSEs), the physiological roles of PrP(C) are still incompletely understood. There is...

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Detaylı Bibliyografya
Asıl Yazarlar: Black, Stefanie A. G., Stys, Peter K., Zamponi, Gerald W., Tsutsui, Shigeki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2014
Konular:
Cell and Developmental Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207032/
https://ncbi.nlm.nih.gov/pubmed/25364752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00045
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