Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes

Hospital- and community-acquired, complicated skin and soft tissue infections, often attributed to Staphylococcus aureus and Streptococcus pyogenes, present a significant health burden that is associated with increased health care costs and mortality. As these two species are difficult to discern on...

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Auteurs principaux: Viswanathan, Kishore, Frey, Kathleen M., Scocchera, Eric W., Martin, Brooke D., Swain III, P. Whitney, Alverson, Jeremy B., Priestley, Nigel D., Anderson, Amy C., Wright, Dennis L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274548/
https://ncbi.nlm.nih.gov/pubmed/22347365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029434
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