Phosphorylation of SRSF1 is modulated by replicational stress

DNA ligase I-deficient 46BR.1G1 cells show a delay in the maturation of replicative intermediates resulting in the accumulation of single- and double-stranded DNA breaks. As a consequence the ataxia telangiectasia mutated protein kinase (ATM) is constitutively phosphorylated at a basal level. Here,...

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Bibliographische Detailangaben
Hauptverfasser: Leva, Valentina, Giuliano, Serena, Bardoni, Anna, Camerini, Serena, Crescenzi, Marco, Lisa, Antonella, Biamonti, Giuseppe, Montecucco, Alessandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273819/
https://ncbi.nlm.nih.gov/pubmed/21984412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr837
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