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DNA Replication Is Intrinsically Hindered in Terminally Differentiated Myotubes

BACKGROUND: Terminally differentiated (TD) cells permanently exit the mitotic cycle while acquiring specialized characteristics. Although TD cells can be forced to reenter the cell cycle by different means, they cannot be made to stably proliferate, as attempts to induce their replication constantly...

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Détails bibliographiques
Auteurs principaux: Pajalunga, Deborah, Puggioni, Eleonora M. R., Mazzola, Alessia, Leva, Valentina, Montecucco, Alessandra, Crescenzi, Marco
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903488/
https://ncbi.nlm.nih.gov/pubmed/20644635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011559
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