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DNA Replication Is Intrinsically Hindered in Terminally Differentiated Myotubes

BACKGROUND: Terminally differentiated (TD) cells permanently exit the mitotic cycle while acquiring specialized characteristics. Although TD cells can be forced to reenter the cell cycle by different means, they cannot be made to stably proliferate, as attempts to induce their replication constantly...

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Hlavní autoři: Pajalunga, Deborah, Puggioni, Eleonora M. R., Mazzola, Alessia, Leva, Valentina, Montecucco, Alessandra, Crescenzi, Marco
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903488/
https://ncbi.nlm.nih.gov/pubmed/20644635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011559
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