A pRb-independent mechanism preserves the postmitotic state in terminally differentiated skeletal muscle cells

In skeletal muscle differentiation, the retinoblastoma protein (pRb) is absolutely necessary to establish definitive mitotic arrest. It is widely assumed that pRb is equally essential to sustain the postmitotic state, but this contention has never been tested. Here, we show that terminal proliferati...

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Detalhes bibliográficos
Main Authors: Camarda, Grazia, Siepi, Francesca, Pajalunga, Deborah, Bernardini, Camilla, Rossi, Rossella, Montecucco, Alessandra, Meccia, Ettore, Crescenzi, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172476/
https://ncbi.nlm.nih.gov/pubmed/15520231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200408164
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