DNA Replication Is Intrinsically Hindered in Terminally Differentiated Myotubes

BACKGROUND: Terminally differentiated (TD) cells permanently exit the mitotic cycle while acquiring specialized characteristics. Although TD cells can be forced to reenter the cell cycle by different means, they cannot be made to stably proliferate, as attempts to induce their replication constantly...

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Main Authors: Pajalunga, Deborah, Puggioni, Eleonora M. R., Mazzola, Alessia, Leva, Valentina, Montecucco, Alessandra, Crescenzi, Marco
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903488/
https://ncbi.nlm.nih.gov/pubmed/20644635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011559
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