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Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry

Methylation of the MLH1 gene promoter region is an underlying cause of colorectal cancer (CRC) with high microsatellite instability (MSI-H) diagnosed in persons without a germline mutation in a mismatch repair (MMR) gene (non-Lynch Syndrome CRC). It is unclear whether relatives of CRC cases with MLH...

詳細記述

保存先:
書誌詳細
主要な著者: Levine, A. Joan, Win, Aung Ko, Buchanan, Daniel D., Jenkins, Mark A., Baron, John A., Young, Joanne P., Long, Tiffany I., Weisenberger, Daniel J., Laird, Peter W., McCall, Rebecca L., Duggan, David J., Haile, Robert W.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273599/
https://ncbi.nlm.nih.gov/pubmed/22144422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0419
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