Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in Ontario

BACKGROUND: Several DNA mismatch repair (MMR) genes, responsible for the majority of Lynch Syndrome cancers, have been identified, predominantly MLH1 and MSH2, but the risk associated with these mutations is still not well established. The aim of this study is to provide population-based estimates o...

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Detalhes bibliográficos
Main Authors: Choi, Yun-Hee, Cotterchio, Michelle, McKeown-Eyssen, Gail, Neerav, Monga, Bapat, Bharati, Boyd, Kevin, Gallinger, Steven, McLaughlin, John, Aronson, Melyssa, Briollais, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744657/
https://ncbi.nlm.nih.gov/pubmed/19698169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-7-14
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