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The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers

There is increased incidence of microsatellite instability (MSI) in patients who develop multiple primary colorectal cancers (CRC), although the association with hereditary nonpolyposis colon cancer (HNPCC) is unclear. This study aims to evaluate the underlying genetic cause of MSI in these patients...

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Detalhes bibliográficos
Main Authors: Lawes, D A, Pearson, T, SenGupta, S, Boulos, P B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361590/
https://ncbi.nlm.nih.gov/pubmed/16106253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602708
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