The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers

There is increased incidence of microsatellite instability (MSI) in patients who develop multiple primary colorectal cancers (CRC), although the association with hereditary nonpolyposis colon cancer (HNPCC) is unclear. This study aims to evaluate the underlying genetic cause of MSI in these patients...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lawes, D A, Pearson, T, SenGupta, S, Boulos, P B
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2005
Sujets:
Molecular Diagnostics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361590/
https://ncbi.nlm.nih.gov/pubmed/16106253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602708
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