Conversion Analysis for Mutation Detection in MLH1 and MSH2 in Patients With Colorectal Cancer

CONTEXT: The accurate identification and interpretation of germline mutations in mismatch repair genes in colorectal cancer cases is critical for clinical management. Current data suggest that mismatch repair mutations are highly heterogeneous and that many mutations are not detected when convention...

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Autors principals: Casey, Graham, Lindor, Noralane M., Papadopoulos, Nickolas, Thibodeau, Stephen N., Moskow, John, Steelman, Scott, Buzin, Carolyn H., Sommer, Steve S., Collins, Christine E., Butz, Malinda, Aronson, Melyssa, Gallinger, Steven, Barker, Melissa A., Young, Joanne P., Jass, Jeremy R., Hopper, John L., Diep, Anh, Bapat, Bharati, Salem, Michael, Seminara, Daniela, Haile, Robert
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933041/
https://ncbi.nlm.nih.gov/pubmed/15713769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.293.7.799
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