Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in Ontario

BACKGROUND: Several DNA mismatch repair (MMR) genes, responsible for the majority of Lynch Syndrome cancers, have been identified, predominantly MLH1 and MSH2, but the risk associated with these mutations is still not well established. The aim of this study is to provide population-based estimates o...

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Detaylı Bibliyografya
Asıl Yazarlar: Choi, Yun-Hee, Cotterchio, Michelle, McKeown-Eyssen, Gail, Neerav, Monga, Bapat, Bharati, Boyd, Kevin, Gallinger, Steven, McLaughlin, John, Aronson, Melyssa, Briollais, Laurent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2009
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744657/
https://ncbi.nlm.nih.gov/pubmed/19698169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-7-14
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