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Ligand Binding and Structural Changes Associated with Allostery in Yeast NAD(+)-specific Isocitrate Dehydrogenase

Yeast NAD(+)-specific isocitrate dehydrogenase (IDH) is an octameric enzyme composed of four each of regulatory IDH1 and catalytic IDH2 subunits that share 42% sequence identity. IDH2 contains catalytic isocitrate/Mg(2+) and NAD(+) binding sites whereas IDH1 contains homologous binding sites, respec...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखक: Lee, McAlister-Henn
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272323/
https://ncbi.nlm.nih.gov/pubmed/22008468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.10.003
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