Crystallization and preliminary X-ray crystallographic analysis of yeast NAD(+)-specific isocitrate dehydrogenase

NAD(+)-specific isocitrate dehydrogenase (IDH; EC 1.1.1.41) is a complex allosterically regulated enzyme in the tricarboxylic acid cycle. Yeast IDH is believed to be an octamer containing four catalytic IDH2 and four regulatory IDH1 subunits. Crystals of yeast IDH have been obtained and optimized us...

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Bibliographic Details
Main Authors: Hu, Gang, Taylor, Alexander B., McAlister-Henn, Lee, Hart, P. John
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2005
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952318/
https://ncbi.nlm.nih.gov/pubmed/16511075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105010651
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