Abnormal Mitochondrial Dynamics and Synaptic Degeneration as Early Events in Alzheimer’s Disease: Implications to Mitochondria-Targeted Antioxidant Therapeutics

Synaptic pathology and mitochondrial oxidative damage are early events in Alzheimer’s disease (AD) progression. Loss of synapses and synaptic damage are the best correlate of cognitive deficits found in AD patients. Recent research on amyloid bet (Aβ) and mitochondria in AD revealed that Aβ accumula...

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Détails bibliographiques
Auteurs principaux: Reddy, P. Hemachandra, Tripathy, Raghav, Troung, Quang, Thirumala, Karuna, Reddy, Tejaswini P., Anekonda, Vishwanath, Shirendeb, Ulziibat P., Calkins, Marcus J., Reddy, Arubala P., Mao, Peizhong, Manczak, Maria
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272314/
https://ncbi.nlm.nih.gov/pubmed/22037588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.10.011
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