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Mre11 regulates CtIP–dependent double strand break repair by interaction with CDK2
Homologous recombination (HR) facilitates accurate repair of DNA double strand breaks (DSBs) during S and G2 phases of the cell cycle by using intact sister chromatids as sequence templates. HR capacity is maximized in S and G2 by Cyclin–Dependent Kinase (CDK) phosphorylation of CtIP, which subseque...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272152/ https://ncbi.nlm.nih.gov/pubmed/22231403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2212 |
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