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BRCA1-CtIP interaction in the repair of DNA double-strand breaks
DNA termini at double-strand breaks are often chemically heterogeneous and require processing before initiation of repair. In a recent report, we demonstrated that CtIP and the MRE11-RAD50-NBS1 (MRN) nuclease complex cooperate with BRCA1 to specifically repair topoisomerase II-DNA adducted breaks. I...
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| Veröffentlicht in: | Mol Cell Oncol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972120/ https://ncbi.nlm.nih.gov/pubmed/27652321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1169343 |
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