Novel Functional MAR Elements of Double Minute Chromosomes in Human Ovarian Cells Capable of Enhancing Gene Expression

Double minute chromosomes or double minutes (DMs) are cytogenetic hallmarks of extrachromosomal genomic amplification and play a critical role in tumorigenesis. Amplified copies of oncogenes in DMs have been associated with increased growth and survival of cancer cells but DNA sequences in DMs which...

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Autors principals: Jin, Yan, Liu, Zheng, Cao, Wei, Ma, Xinying, Fan, Yihui, Yu, Yang, Bai, Jing, Chen, Feng, Rosales, Jesusa, Lee, Ki-Young, Fu, Songbin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272018/
https://ncbi.nlm.nih.gov/pubmed/22319568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030419
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