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Association between sister chromatid exchange and double minute chromosomes in human tumor cells

BACKGROUND: Double minute chromosomes (DMs) are the cytogenetic hallmark of extra-chromosomal genomic amplification. They can well represent the advanced stage of malignancy. However, the mechanisms of DM generation are still not fully understood. Here, the sister chromatid exchange (SCE) was used t...

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Detalhes bibliográficos
Publicado no:Mol Cytogenet
Main Authors: Xu, Jie, Liu, Peng, Meng, Xiangning, Bai, Jing, Fu, Songbin, Guan, Rongwei, Sun, Wenjing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653931/
https://ncbi.nlm.nih.gov/pubmed/26594241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-015-0192-x
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