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Association between sister chromatid exchange and double minute chromosomes in human tumor cells

BACKGROUND: Double minute chromosomes (DMs) are the cytogenetic hallmark of extra-chromosomal genomic amplification. They can well represent the advanced stage of malignancy. However, the mechanisms of DM generation are still not fully understood. Here, the sister chromatid exchange (SCE) was used t...

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Dettagli Bibliografici
Pubblicato in:Mol Cytogenet
Autori principali: Xu, Jie, Liu, Peng, Meng, Xiangning, Bai, Jing, Fu, Songbin, Guan, Rongwei, Sun, Wenjing
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653931/
https://ncbi.nlm.nih.gov/pubmed/26594241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-015-0192-x
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