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Association between sister chromatid exchange and double minute chromosomes in human tumor cells

BACKGROUND: Double minute chromosomes (DMs) are the cytogenetic hallmark of extra-chromosomal genomic amplification. They can well represent the advanced stage of malignancy. However, the mechanisms of DM generation are still not fully understood. Here, the sister chromatid exchange (SCE) was used t...

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Publicat a:Mol Cytogenet
Autors principals: Xu, Jie, Liu, Peng, Meng, Xiangning, Bai, Jing, Fu, Songbin, Guan, Rongwei, Sun, Wenjing
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653931/
https://ncbi.nlm.nih.gov/pubmed/26594241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-015-0192-x
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