Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells

Double minute chromosomes (DMs) are a hallmark of gene amplification. The relationship between the formation of DMs and the amplification of DM-carried genes remains to be clarified. The human colorectal cancer cell line NCI-H716 and human malignant primitive neuroectodermal tumor cell line SK-PN-DW...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Ji, Wei, Bian, Zehua, Yu, Yang, Yuan, Chao, Liu, Yang, Yu, Lisa, Li, Chunxiang, Zhu, Jing, Jia, Xueyuan, Guan, Rongwei, Zhang, Chunyu, Meng, Xiangning, Jin, Yan, Bai, Jing, Yu, Jingcui, Lee, Ki-Young, Sun, Wenjing, Fu, Songbin
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233979/
https://ncbi.nlm.nih.gov/pubmed/24027017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28467
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