Molecular structure and evolution mechanism of two populations of double minutes in human colorectal cancer cells

Gene amplification chiefly manifests as homogeneously stained regions (HSRs) or double minutes (DMs) in cytogenetically and extrachromosomal DNA (ecDNA) in molecular genetics. Evidence suggests that gene amplification is becoming a hotspot for cancer research, which may be a new treatment strategy f...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Jia, Xueyuan, Guan, Rongwei, Cui, Xiaobo, Zhu, Jing, Liu, Peng, Zhang, Ling, Wang, Dong, Zhang, Yang, Dong, Kexian, Wu, Jie, Ji, Wei, Ji, Guohua, Bai, Jing, Yu, Jingcui, Yu, Yang, Sun, Wenjing, Zhang, Feng, Fu, Songbin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754069/
https://ncbi.nlm.nih.gov/pubmed/33124133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16035
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