Molecular structure and evolution mechanism of two populations of double minutes in human colorectal cancer cells

Gene amplification chiefly manifests as homogeneously stained regions (HSRs) or double minutes (DMs) in cytogenetically and extrachromosomal DNA (ecDNA) in molecular genetics. Evidence suggests that gene amplification is becoming a hotspot for cancer research, which may be a new treatment strategy f...

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Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Jia, Xueyuan, Guan, Rongwei, Cui, Xiaobo, Zhu, Jing, Liu, Peng, Zhang, Ling, Wang, Dong, Zhang, Yang, Dong, Kexian, Wu, Jie, Ji, Wei, Ji, Guohua, Bai, Jing, Yu, Jingcui, Yu, Yang, Sun, Wenjing, Zhang, Feng, Fu, Songbin
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754069/
https://ncbi.nlm.nih.gov/pubmed/33124133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16035
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