De novo-generated small palindromes are characteristic of amplicon boundary junction of double minutes

Double minutes (DMs) are hallmarks of gene amplification. However, their molecular structure and the mechanisms of formation are largely unknown. To elucidate the structure and underlying molecular mechanism of DMs, we obtained and cloned DMs using microdissection; and degenerated oligonucleotide pr...

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Detalhes bibliográficos
Main Authors: Zhu, Jing, Yu, Yang, Meng, Xiangning, Fan, Yihui, Zhang, Yu, Zhou, Chunshui, Yue, Zhichao, Jin, Yan, Zhang, Chunyu, Yu, Lisa, Ji, Wei, Jia, Xueyuan, Guan, Rongwei, Wu, Jie, Yu, Jingcui, Bai, Jing, Guan, Xin-Yuan, Wang, Mingrong, Lee, Ki-Young, Sun, Wenjing, Fu, Songbin
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734650/
https://ncbi.nlm.nih.gov/pubmed/23382041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28084
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