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Elevated Rates of Sister Chromatid Exchange at Chromosome Ends

Chromosome ends are known hotspots of meiotic recombination and double-strand breaks. We monitored mitotic sister chromatid exchange (SCE) in telomeres and subtelomeres and found that 17% of all SCE occurs in the terminal 0.1% of the chromosome. Telomeres and subtelomeres are significantly enriched...

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Detalhes bibliográficos
Main Authors: Rudd, M. Katharine, Friedman, Cynthia, Parghi, Sean S, Linardopoulou, Elena V, Hsu, Li, Trask, Barbara J
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802831/
https://ncbi.nlm.nih.gov/pubmed/17319749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030032
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