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Reducing system noise in copy number data using principal components of self-self hybridizations

Genomic copy number variation underlies genetic disorders such as autism, schizophrenia, and congenital heart disease. Copy number variations are commonly detected by array based comparative genomic hybridization of sample to reference DNAs, but probe and operational variables combine to create corr...

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書誌詳細
主要な著者: Lee, Yoon-ha, Ronemus, Michael, Kendall, Jude, Lakshmi, B., Leotta, Anthony, Levy, Dan, Esposito, Diane, Grubor, Vladimir, Ye, Kenny, Wigler, Michael, Yamrom, Boris
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271883/
https://ncbi.nlm.nih.gov/pubmed/22207624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106233109
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