Reducing system noise in copy number data using principal components of self-self hybridizations

Genomic copy number variation underlies genetic disorders such as autism, schizophrenia, and congenital heart disease. Copy number variations are commonly detected by array based comparative genomic hybridization of sample to reference DNAs, but probe and operational variables combine to create corr...

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Библиографические подробности
Главные авторы: Lee, Yoon-ha, Ronemus, Michael, Kendall, Jude, Lakshmi, B., Leotta, Anthony, Levy, Dan, Esposito, Diane, Grubor, Vladimir, Ye, Kenny, Wigler, Michael, Yamrom, Boris
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2012
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271883/
https://ncbi.nlm.nih.gov/pubmed/22207624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106233109
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