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Genome wide copy number analysis of single cells

Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells, where information regarding genetic heterogeneity is lost. Here, we present a protocol that allows for the g...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Baslan, Timour, Kendall, Jude, Rodgers, Linda, Cox, Hilary, Riggs, Mike, Stepansky, Asya, Troge, Jennifer, Ravi, Kandasamy, Esposito, Diane, Lakshmi, B., Wigler, Michael, Navin, Nicholas, Hicks, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069701/
https://ncbi.nlm.nih.gov/pubmed/22555242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2012.039
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