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Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications
Histone deacetylases (HDACs) affect cell growth at the transcriptional level by regulating the acetylation status of nucleosomal histones. HDAC inhibition induces differentiation and/or apoptosis in transformed cells. We recently showed that HDAC inhibitors, such as suberoylanilide hydroxamic acid (...
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| Hoofdauteurs: | , , , , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327183/ https://ncbi.nlm.nih.gov/pubmed/14695887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536759100 |
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