Digital Detection of Genetic Mutations Using SPC-Sequencing

Deletion or insertion mutations lead to a frameshift that causes misalignment between wild-type and mutated allele sequences, making it difficult to identify such mutations unambiguously by using electrophoresis-based DNA sequencing. We have previously established the feasibility of an accurate DNA...

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Εκδόθηκε σε:	Genome Res
Κύριοι συγγραφείς:	Ruparel, Hameer, Ulz, Michael E., Kim, Sobin, Ju, Jingyue
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Cold Spring Harbor Laboratory Press 2004
Θέματα:	Methods
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327105/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14762066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.1344104
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