Digital Detection of Genetic Mutations Using SPC-Sequencing
Deletion or insertion mutations lead to a frameshift that causes misalignment between wild-type and mutated allele sequences, making it difficult to identify such mutations unambiguously by using electrophoresis-based DNA sequencing. We have previously established the feasibility of an accurate DNA...
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| Veröffentlicht in: | Genome Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2004
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327105/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14762066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.1344104 |
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