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The Enzymatic Activity of Lysyl Oxidas-like-2 (LOXL2) Is Not Required for LOXL2-induced Inhibition of Keratinocyte Differentiation

Lysyl oxidase-like-2 (LOXL2) induces tumor progression and fibrosis. It also inhibits the differentiation of keratinocytes promoting development of squamous cell carcinomas. Stimulation of HaCaT skin keratinocytes with exogenous LOXL2 or overexpression of LOXL2 in these cells inhibits their differen...

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Detalhes bibliográficos
Main Authors: Lugassy, Jennie, Zaffryar-Eilot, Shelly, Soueid, Sharon, Mordoviz, Amit, Smith, Victoria, Kessler, Ofra, Neufeld, Gera
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271007/
https://ncbi.nlm.nih.gov/pubmed/22157764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.261016
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