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The Enzymatic Activity of Lysyl Oxidas-like-2 (LOXL2) Is Not Required for LOXL2-induced Inhibition of Keratinocyte Differentiation

Lysyl oxidase-like-2 (LOXL2) induces tumor progression and fibrosis. It also inhibits the differentiation of keratinocytes promoting development of squamous cell carcinomas. Stimulation of HaCaT skin keratinocytes with exogenous LOXL2 or overexpression of LOXL2 in these cells inhibits their differen...

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Détails bibliographiques
Auteurs principaux: Lugassy, Jennie, Zaffryar-Eilot, Shelly, Soueid, Sharon, Mordoviz, Amit, Smith, Victoria, Kessler, Ofra, Neufeld, Gera
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271007/
https://ncbi.nlm.nih.gov/pubmed/22157764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.261016
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