Lysyl oxidase–like 2 (LOXL2)–mediated cross-linking of tropoelastin

Lysyl oxidases (LOXs) play a central role in extracellular matrix remodeling during development and tumor growth and fibrosis through cross-linking of collagens and elastin. We have limited knowledge of the structure and substrate specificity of these secreted enzymes. LOXs share a conserved C-termi...

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Bibliographic Details
Published in:FASEB J
Main Authors: Schmelzer, Christian E. H., Heinz, Andrea, Troilo, Helen, Lockhart-Cairns, Michael P., Jowitt, Thomas A., Marchand, Marion F., Bidault, Laurent, Bignon, Marine, Hedtke, Tobias, Barret, Alain, McConnell, James C., Sherratt, Michael J., Germain, Stéphane, Hulmes, David J. S., Baldock, Clair, Muller, Laurent
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2019
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629125/
https://ncbi.nlm.nih.gov/pubmed/30676771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801860RR
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