Lysyl oxidase–like 2 (LOXL2)–mediated cross-linking of tropoelastin

Lysyl oxidases (LOXs) play a central role in extracellular matrix remodeling during development and tumor growth and fibrosis through cross-linking of collagens and elastin. We have limited knowledge of the structure and substrate specificity of these secreted enzymes. LOXs share a conserved C-termi...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Schmelzer, Christian E. H., Heinz, Andrea, Troilo, Helen, Lockhart-Cairns, Michael P., Jowitt, Thomas A., Marchand, Marion F., Bidault, Laurent, Bignon, Marine, Hedtke, Tobias, Barret, Alain, McConnell, James C., Sherratt, Michael J., Germain, Stéphane, Hulmes, David J. S., Baldock, Clair, Muller, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629125/
https://ncbi.nlm.nih.gov/pubmed/30676771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801860RR
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