Lysyl oxidase–like 2 (LOXL2)–mediated cross-linking of tropoelastin

Lysyl oxidases (LOXs) play a central role in extracellular matrix remodeling during development and tumor growth and fibrosis through cross-linking of collagens and elastin. We have limited knowledge of the structure and substrate specificity of these secreted enzymes. LOXs share a conserved C-termi...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Schmelzer, Christian E. H., Heinz, Andrea, Troilo, Helen, Lockhart-Cairns, Michael P., Jowitt, Thomas A., Marchand, Marion F., Bidault, Laurent, Bignon, Marine, Hedtke, Tobias, Barret, Alain, McConnell, James C., Sherratt, Michael J., Germain, Stéphane, Hulmes, David J. S., Baldock, Clair, Muller, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629125/
https://ncbi.nlm.nih.gov/pubmed/30676771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801860RR
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