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Dormant tumor cells expressing LOXL2 acquire a stem-like phenotype mediating their transition to proliferative growth
Recurrence of breast cancer disease years after treatment appears to arise from disseminated dormant tumor cells (DTC). The mechanisms underlying the outgrowth of DTC remain largely unknown. Here we demonstrate that dormant MCF-7 cells expressing LOXL2 acquire a cancer stem cell (CSC)-like phenotype...
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| Vydáno v: | Oncotarget |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342084/ https://ncbi.nlm.nih.gov/pubmed/27655685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12109 |
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