‘Normalizing' the malignant phenotype of luminal breast cancer cells via alpha(v)beta(3)-integrin

Reestablishing tissue organization of breast cancer cells into acini was previously shown to override their malignant phenotype. In our study, we demonstrate that alpha(v)beta(3) integrin (Int-αvβ3), previously shown to play a role in cancer progression, promoted differentiation and growth arrest of...

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Publicado en:Cell Death Dis
Autores principales: Abu-Tayeh, Hanan, Weidenfeld, Keren, Zhilin-Roth, Alisa, Schif-Zuck, Sagi, Thaler, Sonja, Cotarelo, Cristina, Tan, Tuan Z, Thiery, Jean P, Green, Jeffrey E, Klorin, Geula, Sabo, Edmond, Sleeman, Jonathan P, Tzukerman, Maty, Barkan, Dalit
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260995/
https://ncbi.nlm.nih.gov/pubmed/27906177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.387
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